Isosorbide Dinitrate and Hydralazine Hydrochloride Tablets

Isosorbide dinitrate and hydralazine hydrochloride tablets are a combination medication used to treat heart failure in certain individuals, particularly in African American patients with symptomatic heart failure despite standard treatments.

Isosorbide dinitrate is a nitrate that works by dilating blood vessels, reducing the workload on the heart, and improving blood flow by relaxing and widening the blood vessels.

Hydralazine hydrochloride is a direct-acting vasodilator that relaxes and widens the blood vessels by affecting the smooth muscles in the walls of the arteries, reducing the resistance against which the heart pumps.